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HCV SVR

Sep 30, 2017

Good afternoon Dr.,

This is just a general question about hepatitis c svr - why is it that SVR determined at the 12 week or greater mark? Is 6 weeks too early? It kind of reminds me of the window testing period of hiv.

Response from Dr. Holodniy

The interval after completing HCV treatment, which predicts long term sustained virologic response (SVR) has been studied at intervals of 4, 12, and 24 weeks after completing treatment. 12 weeks was considered the sweet spot, where 4 weeks was too early, as some relapsers were found, and waiting until 24 weeks after stopping treatment was not anymore predictive of SVR than 12 weeks.



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