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HIV being a retrovirus
Oct 27, 2013

How is it that HIV kills t-cells when retroviruses do not kill the host cells they infect?

Response from Dr. Holodniy

Although the complete mechanisms have yet to be fully elucidated, there is now evidence that when HIV gets into CD4 cells these cells become activated and are then programmed to die prematurely. In addition, at the point of when HIV is getting integrated into cell DNA, host cell enzymes are activated that also lead programmed cell death.



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