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HIV and asymptomatic raised alkaline phosphatase level

Oct 20, 2013

39 year old chronic alcoholic with HIV present with tuberculous consolidation with effusion whose CD4 count was 223/mm3 has asymptomatic raised alkaline phosphatase level. Total bilirubin and AST was twice the normal but ALT was within normal limit. Serum calcium and phosphate was normal. No history of fracture. No features of lymphoma and any other intra abdominal lymphadenopathy. No bile duct dilatation. Which can be the cause of his raised alkaline phosphatase level? Any suggestion or advice?

Response from Dr. Holodniy

An elevated serum alkaline phosphatase level is a non-specific finding that can be associated with liver or biliary disease, bone disease, cancers, and other medical conditions, including active tuberculosis infection.

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