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HIV Test
Aug 25, 2013

What does a CD4 count of 140, in a normal range of 330-1100 mean? How can I calibrate it to a normal range of 550-1500? Also, a cd4 as a percent of cd3 if it is 18 then what does it mean? Lastly, a cd4/cd8 ratio of 0.24 means what?

Response from Dr. Holodniy

Although you don't indicate what your HIV viral load result is or whether you are receiving HIV treatment, that CD4 count as you know is low. It would be difficult to compare that number in the context of the other range. In people with HIV infection, the CD4 count declines and the CD8 count increases in reaction to the infection. That is why the CD4/CD8 ratio is low and in most uninfected people is usually between 1 and 2. CD3+ cells are all t lymphocytes including CD4+ and CD8+ cells. Usually they are evenly split around 50% each. So a CD4% of 18% is low, and goes along with the low ratio and low CD4 count.



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