The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

Understanding Your LabsUnderstanding Your Labs
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  • Email Email
  • Glossary Glossary

Detectable Viral Load last 2 test

May 5, 2013

Dear Doctor,

Poz since 1997, have been on numerous combos and have some resistance, was on Kaletra, Combivir, Viread and on this combo for 6 years and undetectable, tcells at about 800. Made a change August 2012 to Isentress, Prezista Norvir, 1st VL in 10-2012 Undetectable, Tcells 725. but the last tests came back detectable in 03-13 VL 97, tcells 877, and my last test on 04-27-13 VL 48. I feel extremely concerned of having detectable VL with these new medications, maybe it's not enough meds for someone with prior resistance, should we add something? Thank you for your comments

Response from Dr. Holodniy

Perhaps. Not knowing your previous resistance results, and your viral load is too low to get a resistance test at this point, it is hard to know whether this is just insignificant blipping or something to be concerned about. It is interesting that you were taking Kaletra and 3 NRTIs (combivir and viread) and were stable, and then dropping the NRTIs for an integrase inhibitor now possibly changed the equation. It would be unlikely that you had integrase resistance before starting. I don't know whether you had any protease inhibitor resistance before that could be affecting the prezista activity. The isentress should be more than enough to make up for the 3 NRTI's you were taking previously, particularly if you did not have any resistance to them. I wouldn't do anything yet and get another test or two to see where the trend is going. But I have found that sometimes you have to add an NRTI back to mix if you are not getting the desired effect.

Hep B Results Borderline Question
I have been hiv poz for 12 years but no med

  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint