Advertisement
The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol
  Breaking News: FDA Approves Triumeq, New Once-Daily Combination Pill
   
Ask the Experts About

Understanding Your LabsUnderstanding Your Labs
           
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  
  • Email Email
  • Glossary Glossary


Three Questions...
May 5, 2001

Hello Dr. Mark,

1) Are t-cells gained during HAART as effective as ones lost pre-treatment? 2) Is a six month lab interval reasonable enough with a t-cell count >1000 and vl <50? 3) What VL is necessary to provoke a serious immune response (sans HAART)...1,000? 10,000? Baseline?

Thanks as always, You are the best!!

Response from Dr. Holodniy

Great questions, hard to answer. #1. You would have to know the immune functional status of a person before infection, to answer this question directly. YOu would have to know how many cells they had and how effective their immune response was to various antigens, and then see if they were lost, and then regained after HAART. We do know that some response returns after treatment starts. Like against CMV and other kinds of infections. It unfortunately doesn;t come back against HIV specific antigens. #2. Yes to see increases or return against those antigens measured as described in #1. #3. I don't think those folks doing these studies have looked at the question in this kind of fine detail. And again is the question about other antigens or HIV specific antigens. The whole issue about treatment interrruptions is that having the viral load pop back up from being <50, allows the cytotoxic t cell response to reemerge. What level of viral load accomplishes this is currently unknown. MH



Previous
haveing false vdrl?
Next
Thalassemia Correction?

  
  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS


 
Advertisement



Q&A TERMS OF USE

This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint

Advertisement