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Changes in T Cells
Dec 16, 2012

I was recently diagnosed with a Tcell count of 144 and a VL of 54,000 started on Atripla right away. 6 weeks later I had a VL of 251 and my T Cells shot up to 501 ... Most recently I have a VL that is UD but my TCells are back down 241 ... Can you help me understand how this could happen. I have not had the flu/cold or anything. Also I Just had a TB test and pneumonia vaccine ... Would this make the T Cells drop even more??

Response from Dr. Holodniy

Another number to follow is the CD4 percent. What was the CD4% result for both of these values? It is usually a more stable number over time and I suspect still remains increased compared to the value before you started HIV treatment. Given that your viral load is undetectable, you have still had a great treatment response. It is hard to know what one value like this means, if as you say, you haven't had any other ongoing medical conditions or vaccinations. I tend to discount the results, particularly if the viral load remains undetectable and the CD4 percent is stable, and wait to see what the next set of numbers looks like.



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