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CD4% and CD4 Count Discordance?

Aug 5, 2012

Dear Mark,

I just came from receiving my third results after being diagnosed in January. I'm not in treatment yet.

These are my results:

January - CD4 689, CD4% 26%, VL 1000 April - CD4 501, CD4% 24%, VL 4000 July - CD4 813, CD4% 19%, VL 3225

My concern is about the CD4% which seems to be decreasing significantly even though my absolute CD4 count has been relatively high and stable. I know the CD4% is meant to be the more stable number and so I'm obviously worried about this, since this might mean that the HIV is actually progressing at a fast pace, while the CD4 count is just fluctuating.

I have read you say that a normal CD4 count is >500 and a normal CD4% is between 30%-35%. I fulfill the former but not the latter and this worries me.

Greetings from the UK and thank you in advance for your advice,

Response from Dr. Holodniy

Yes, the trend is concerning. I would recommend starting HIV treatment.

should i start medication although viral load is undetectable?
undetectable vs. detected but too low to count

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