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Atripla & Probiotics

Jun 17, 2012

Dear Doctor I have been taking Atripla for 5 years i have had NO side affects i have been very lucky that way in terms of treatment!!! My (CD4% is 48/1500) & my (VL is below 20 copies/Undetectable).

I have taken a 50 billion probiotic capsule everyday since 2008 thats 4 years, obviously there has been no interaction between the Atripla & Probiotic capsule as my counts are excellent but i have been reading on the internet through medical blogs that probiotics actually increase t-cell population & one blog said if you combine probiotics together with HAART or other meds like Bactrim DS or Zithromax the benefits can be staggering as long as the probiotic is taken 8 hrs before or after the DAILY regimen . Is there any research in the HIV field to back this up?

Response from Dr. Holodniy

There have been several small (some placebo controlled) studies, which suggest in the short term (a few weeks of study) that probiotic administration (either as yogurt or in capsule form) can result in CD4 count increases. There is significant damage in the gut as a result of HIV infection. Whether probiotic administration corrects the situation and removes the ongoing damage is still under study.

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