DEAR DOCTOR HOLODINDY, GOOD MORNING & HAVE A GOOD DAY, CONGRATS ON RUNING SUCH A VALUABLE SERVICE FOR THE HUMANITY. MY WIFE GOT HEP B INFECTION ON THE DELIVERY, HER DETAILS ARE AS UNDER, AGE: 25 YEARS, REGION : ASIA HEP B SURF ANTIGEN: 40,000 (REACTIVE) CUT OFF VALUE 1.0 HCV SCREENING : 0.21 (NON-REACTIVE) CUT OFF VALUE 1.0 ANTIE HBe : +VE (LAB DIDN'T GIVE ME A VALUE) ANTI HBc : +VE (LAB DIDN'T GIVE ME A VALUE) HBeAg : NEGATIVE IgM ANTIBODY TO HEP B CORE ANTIGEN: NEGATIVE HBV DNA (REAL TIME): 369 IU/ML (IU= 5 COPIES) ALT : 27 (5 MONTHS BACK IT WAS 31) PLZ, TELL ME THAT A) DO SHE NEED AN ANTIVIRAL TREATMENT? B) HER HEP B IS CHRONIC OR ACUTE? c) WHAT IS THE POSSIBLE TREATMENT IN YOUR OPINION? THANKS & REGARDS,

Given the low HBV DNA level and negative HBV e antigen test, many providers would not recommend treatment at this point. Given the negative IgM core antibody test, the infection is likely chronic. There are several medications that are active against HBV. You need to consult a liver specialist to see whether treatment is indicated now and with what medication.