Dec 25, 2011
Would someone with Th2 dominace prior to HIV infection tend to have a worse prognosis compared to someone with Th2 dominace?
| Response from Dr. Holodniy
It's a great question. I am not sure I could answer it, as I don't know what data there is where people have had their Th1 and Th2 characteristics identified before they are HIV infected and then again afterwards. Profiling these responses has certainly been done in people without HIV infection who have asthma and other diseases for example. As you may know there is a change in many people people from a primarily Th1 response (inflammatory/cytotoxic) to a Th2 response (anti-inflammatory) that has been implicated in HIV disease progression. Whether people who already have a predominant Th2 response and then become HIV infected progress more quickly, or whether HIV infection induces a change to a Th1 response after acute infection, even in those with a predominant Th2 pre-infection response is probably not known.
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.