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low WBC at 2.7 for long period despite taking atripla.
Jun 19, 2011

Why has my WBC count remained so low for a decade now without significant change? The only change was from 2.5 to 2.7 despite taking HIV medicine and maintaining an undetectable VL and CD4 at just around 200s to 300s. Please explain.

Response from Dr. Holodniy

Although you don't indicate what your baseline CD4 count was before starting HIV treatment, whether you had any prior serious opportunistic infections, or whether this low WBC was ever worked up (i.e. bone marrow biopsy), we do see people who may have had advanced HIV infection prior to starting treatment where the HIV infection or other ongoing infections or malignancies have resulted in a stable but decreased WBC. Sometimes the WBC count recovers and sometimes it does not.



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