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Western Blot results

Jun 5, 2011

My WB was abnormal and positive. GP160 AB(Abnormal)Present, GP120 AB(Abmormal)Present, P65 AB Equivocal, P55 AB(Abmormal) Present, P51 AB(Abnormal) Present, GP41 AB(Abnormal) Present, GP40 AB(Abnormal) Present, P31 AB(abnormal) Present, P24 AB(Abnormal) Present, P18 AB Absent. Also my HIV 1/0/2 ABS index value is >50.00(H). (Index Value: Specimen reactivity related to the negative cutoff.) My internist told me this is an HIV positive result and is sending me to an infectionous disease specialist. Can you tell me what the test and the presence of these antibodies means? I am looking for some direction and information on what this all means.

Response from Dr. Holodniy

Since both the screening HIV antibody test and the confirmatory antibody test are positive, this confirms an HIV diagnosis. The different "abnormal" or "present" results from the western blot indicate that your body has made antibodies against these proteins contained within the HIV virus, which would not be present if you had not been exposed to the virus. The specialist will order a bunch of other tests, including a CD4 count (a measure of how damaged or not your immune system is) and a viral load test (which indicates how much virus you may have being produced or circulating in your blood). From there a decision regarding treatment will be made.

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