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Hep B surface antigen (HBsAg) negattive but Hep B surface antibody (Anti-HBs) reactive
May 29, 2011

my father had chronic hepatisis B infection. He is under medication of Sevivo. 6 month ago his Hep B surface antigen (HBsAg)& DNA but his Hep B surface antibody (Anti-HBs)is still showing reactive. How long does it take for the antibody to develop. He is still under medication.Request advise

Response from Dr. Holodniy

It is not clear from your message whether the HBV surface antigen and DNA are still positive and the surface antibody is negative. Sometimes it takes many months for the surface antigen and DNA to become negative, and the antibody may or may not become positive. But treatment should be continued.



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