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relationship of Viral load and CD4 count
Feb 20, 2011

My granddaughter (aged 4years) has been diagnosed as HIV positive. She was on ARV treatment, but on the death of our daughter we had no information available beyond this. We organised tests and in October 2010 she had a CD4 count of 735 and a viral load of around 400/ml. Her treatment was adjusted. Early February 2011 she was re-tested and the viral load is undetected (<40/ml) but the CD4 count is down to 360 -- while it is true that at the time of her second test she was recovering from a (not severe) ear/throat infection which is perhaps the explanation, I feel very worried and would like to know how this dramatic change was possible.

Response from Dr. Holodniy

It seems unlikely that with a change in HIV meds that resulted in here viral load becoming undetectable, that she would have experienced such a decline in CD4 count unless something else was going. The ear infection is a plausible reason for the observation, and suspect that when you take her in again her CD4 count will be back up.



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