Apr 17, 2010
One of my patients (diagnosed 2006), also co-infected with Hepatitis C had good CD4 counts >1000 until recently when CD4 has plunged to 61. Viral load has never gone beyond 71 copies. Patient has led a chaotic lifestyle in having regular bloods taken but last three VL's have been undetectable with no treatment! At last visit he presented with extensive pral candidiasis and flare up of psoriasis. he was placed on co-trimoxazole and fluconazole including preparations for the psoriasis.Clearly he now requires HAART, can you explain this? I always believed elite controllers also maintained a high CD4 response.
| Response from Dr. Holodniy
I have never seen a real CD4 count decline from 1000 to 61 in such a short time frame. Did you repeat it? Given your description of oral candidiasis (in the absence of any antimicrobial administration) this would indicate some likely immunologic perturbation with loss of immunologic control. Is is also curious though, despite such a crash in CD4 count and symptomatic disease that the viral load has not increased. Some anecdotal cases have occurred with superinfection with another HIV strain leading to disease progression, but again I would have expected to see a viral load response to match the CD4 cell decline.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Oral Ulcers After Sharing Dildos Sign Of HIV AIDS
- Painful Red Spots After Receiving Oral Sex Worried I Have HIV
- Swollen Lymph Glands After Vaginal Sex Condom Broke Worried I Have HIV
- Tingling In Feet After Unprotected Vaginal Sex Worried I Have HIV
- Tingling Lips After Handjob Worried I Have HIV
- After Being Exposed To Hpv How Long Does It Take For Signs Of Cervical Cancer To Appear
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.