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Apr 17, 2010

what are the underlying phathophisiology behind IRIS ? what treatment options are there in relation to modulating our immune response and other options? Is there any relation between CD4 cells proliferation and IRIS? Thank you.

Response from Dr. Holodniy

IRIS is usually an immunologic response to preexistent infectious agents within a few weeks of starting HIV meds. It is the result of the immune system being reconstituted and t cells now recognizing that these pathogens are present and want to do something about it. Depending on the condition, antibiotics, steroids, or nothing may need to be done.

increase in viral load
elite controller?

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