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Dropping cd4 and increasing VL
Mar 21, 2010

Hello Doc and thanks for all your patience in answering all our questions; I am wondering what is happening..so far my VL has remained undetectable and my CD4 has been over 1000..however in the last 2 years i have noticed a drop in the CD4 and an increase of the VL..last report was 198 copies.I know this are good results especially i am not on any medications but my concern is that it looks that my immune system is weakening...am afraid that the downtrend will continue...

Please advise...below are my results from 2002- 2010...

03/08/2010 CD4 Count 1160 cells/mm3bb 03/08/2010 Hemoglobin (HgB) 14.3 g/dLbb 03/08/2010 Hematocrit (HCT/Packed Cell Volume/PCV) 41.2 %bb 03/08/2010 Hematocrit (HCT/Packed Cell Volume/PCV) 41.2 %bb 03/08/2010 Platelet Count (Thrombocyte Count) 266 platelets/Lbb 03/08/2010 Red Blood Cell Count (RBC) 4.64 RBCs/Lbb 03/08/2010 White Blood Cell Count (WBC/Leukocyte Count) 8.2 cells/mcLbb 03/08/2010 White Blood Cell Count (WBC/Leukocyte Count) 8.2 cells/mcLbb 03/08/2010 Viral Load (HIV) (HIV RNA) 198 copies/mLbb 08/25/2009 White Blood Cell Count (WBC/Leukocyte Count) 7.91 cells/mcLbb 08/25/2009 Hemoglobin (HgB) 13.9 g/dLbb 08/25/2009 Hematocrit (HCT/Packed Cell Volume/PCV) 41 %bb 08/25/2009 Platelet Count (Thrombocyte Count) 258 platelets/Lbb 08/25/2009 Red Blood Cell Count (RBC) 4.5 RBCs/Lbb 08/25/2009 Viral Load (HIV) (HIV RNA) 160 copies/mLbb 08/25/2009 CD4 Count 1101 cells/mm3bb 07/29/2008 White Blood Cell Count (WBC/Leukocyte Count) 8900 cells/mcLbb 07/29/2008 Hematocrit (HCT/Packed Cell Volume/PCV) 48 %bb 07/29/2008 Hematocrit (HCT/Packed Cell Volume/PCV) 48 %bb 07/29/2008 Hemoglobin (HgB) 15.5 g/dLbb 07/29/2008 Platelet Count (Thrombocyte Count) 287 platelets/Lbb 07/29/2008 Red Blood Cell Count (RBC) 4.87 RBCs/Lbb 07/29/2008 Viral Load (HIV) (HIV RNA) 0 copies/mLbb 07/29/2008 CD4 Count 1202 cells/mm3bb 11/25/2006 Viral Load (HIV) (HIV RNA) 0 copies/mLbb 11/25/2006 CD4 Count 1259 cells/mm3bb 12/08/2004 Viral Load (HIV) (HIV RNA) 0 copies/mLbb 12/08/2004 CD4 Count 1347 cells/mm3bb 11/24/2003 Viral Load (HIV) (HIV RNA) 0 copies/mLbb 11/24/2003 CD4 Count 1494 cells/mm3bb 07/21/2003 White Blood Cell Count (WBC/Leukocyte Count) 11600 cells/mcLbb 07/21/2003 Viral Load (HIV) (HIV RNA) 0 copies/mLbb 07/21/2003 CD4 Count 1466 cells/mm3bb 09/02/2002 Viral Load (HIV) (HIV RNA) 190 copies/mLbb 09/02/2002 CD4 Count 1110 cells/mm3bb 04/02/2002 Viral Load (HIV) (HIV RNA) 430 copies/mLbb 04/02/2002 CD4 Count 1130 cells/mm3bb 01/24/2002 CD4 Count 1114 cells/mm3bb Best Regards, Vick

Response from Dr. Holodniy

Although you don't report your CD4 percent, I suspect they have not changed. I am not concerned that there is any real CD4 decline or that now a very low but detectable viral load is present.



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