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| Did I make a huge mistake? Nov 14, 2009 After 10 years of undetectable viral load lab results, my last test result indicated my vl was 2300. My original treatment was Sustiva/Combivir but I switched to Atripla a few years back for simplified dosing only. When my doctor saw my test result with vl of 2300, she told me to stop taking my meds for 10 days while they performed a geno test on my previous blood test to determine which of the meds I was resistant to. NOW the geno test has come back NEGATIVE - meaning I am not resistant to any of the components of Atripla so she has started me back on the Atripla. Am I at a GREATER risk for resistance now that she had me stop my meds for 10 days? Was I given bad advice? Should I have ignored her advice and continued taking my meds while having the lab test retaken? |
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Response from Dr. Holodniy
I am not sure I would have recommended stopping your meds to get the genotype. A viral load of 2300 is high enough to do a resistance test, and it is usually better to get the resistance test while you are on medications. You will soon see whether restarting atripla results in getting back to an undetectable viral load. If it does not, I would recommend another resistance test while on treatment to see what is really going on. It is unlikely that a 10 day gap would result in the development of resistance. | ||||||||||
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