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haart therapy and hiv genes
Oct 25, 2009

Of the nine HIV genes, which one according to HAART therapy would be the most dangerous if it were to mutate?

Response from Dr. Holodniy

Almost all HIV drugs work on HIV enzymes (reverse transcriptase and protease) that are co-located in the HIV-1 pol gene. Mutations in the gene sequences coding for these enzymes are known to cause drug resistance and therefore failure of many HIV medication regimens.



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