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RPR
Sep 20, 2009

I tested positive for Syphilis for a few years. On my last RPR my physician said it looked as if I was reinfected, or might have "chronic syphilis." I got my results of my last RPR after the 3 consecutive treatments of penicillin and my RPR went from 1:4 to a 1:2. Is that a dramatic enough decrease? I know physicians should seek a 4 fold decrease, so a 1:1 would be ideal, but is a 1:2 ok?

Response from Dr. Holodniy

I don't know what chronic syphilis means. It appears that you likely had latent syphilis and received the appropriate treatment. The RPR titer may remain positive for years or forever, even after successful treatment. So if you are starting at 1:4 you may or may not see any further decline.



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