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I need help understanding hep b serum lab tests
Aug 29, 2009

I am a chronic hep b carrier. I have genotype a. My viral load was around 300,000,000 copies. I was also e-antigen positive until recently. I took telbivudine for one year, and I had undetectable dna, and the surface antibody test indicated seroconversion. However, another viral load taken about 90 days after I stopped taking telbivudine was about 100,000 copies. Now I am e-antigen negative, and e-antigen antibody positive, (positive abnormal) and the HBV ultraqual is positive. My lft's are normal now, but i am confused about the status of my liver disease- my biopsy showed stage 2, to stage 3, 3 years ago. Am I at a greater risk of hepatocellular carcinoma now? Has the virus mutated?

Response from Dr. Holodniy

YOu need to reconsult with the liver specialist, but I think that restarting treatment is likely what you need to do.



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