HIV attacks CD8? CD3?
Aug 9, 2009
Does HIV infect cd8 or cd3 white blood cells, or affect them? I know all about HIV on cd4, but there isn't much out there about CD3 and 8's. Thanks for answering!
Response from Dr. Holodniy
Unlikely to infect CD8 cells, unless they are dual positive CD4/CD8, of which there are a few. On the other hand, infecting CD4 cells and destroying them does affect CD8 function, in that CD4 cells are important in signaling CD8 cells to function effectively. CD3 + cells are all t lymphocytes, of which CD3+CD4+ cells are the CD4 cells we speak about.
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