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Primary/acute infection and labs
Dec 21, 2008

Dear Dr. Holodniy,

I was first diagnosed with HIV infection about a month ago. I experienced a typical sickness (fever, achey, headache, fatigue, etc.) November 14-19 and saw my doctor on the 19th when she did various HIV tests. I got the results a week later on the 26th. My viral load was more than 10 million and did not have measurable antibodies. I don't believe I have seroconverted even yet. The tests taken on the 26th showed the same viral load and a CD4 count of 681, CD4 % of 34.

About a week later, Dec. 4, I had tests taken again. I do not have the viral load yet but my CD4s had dropped by half--count of 323 and percentage of 17.03. I was tested again on Dec. 9 and had a CD4 number of 311 and percentage of 18.89.

What are your thoughts on my very high viral load and the dramatic drop in my CD4s?

Thanks,

PS: I have enrolled under a treatment study for people in primary/acute infection--thats why I have had so many tests.

Response from Dr. Holodniy

The very high viral load and CD4 count decline are very consistent with acute HIV infection.



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