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question on Dr. H. reply on 6/15

Jun 22, 2008

In ref, to : " In general, the ratio inverts somewhat later as well, when chronic infection in the face of ongoing viral replication starts to destroy CD4 cells and the body's response is also to increase the CD8 count. "

If at years 4, 5,and 6 post infection the cd4/cd8 ratio is consistently at 1.5 or 1.6, with cd4 percentages at 37%, 38% and 38% , and cd4 abs between 500 and 630 ( at 9 am test time ) and as noted above cd8s at roughly half of those cd4 counts, does that reflect an elite controller/non-progressor, or is 6 years too early for the cd8 ratio to be inverted and one can expect this in years 6 to 10 or even later ? Kind thanks

Response from Dr. Holodniy

You don't indicate what your viral load is. Assuming it is < 1,000, then yes, those numbers look like someone whose immune system can control the virus.

How much can %CD4 jump and be considered accurate?

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