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kaletra/truvada or viramune/truvada

Jun 8, 2008

After 7 years of being diagnosed with HIV now my CD4 97, VL 23,000, resistance test came back negative. I'm on bactrim, no oportunistic infections ever or any other illness, all other labs within normal ranges. My doctor advised me to take kaletra/truvada based on my low cd4 y prefer viramune/truvada first and make adjustments to treatment in the future. What do u think is best for me?

Response from Dr. Holodniy

Your viral load is of a moderate level and most regimens should get you down to an undetectable level. A recent study comparing kaletra and efavirenz (a cousin of nevirapine) combined with drugs like truvada demonstrated that efavirenz regimens got more people to undetectable compared to kaletra; however, those on efavirenz were more likely to develop HIV drug resistant virus if they failed on a regimen compared to those who received kaletra. Kaletra was not compared to nevirapine containing regimens. One advantage of efavirenz with truvada is that it now comes all together as one pill (Atripla) that you take once daily.

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