|correlation of vl level to cd4,cd8, other
Jan 18, 2008
Dear Dr, Without the help of any medication would a moderate to high VL GENERALLY cause a moderate or higher cd8 count and % , with inverted cd8/cd4 ratio, and would the opposite ( a lower or undetectable VL ) causing a low or normal cd8 ) be true ? Also, does the VL level impact cd4% in similar manner; a higher VL resullting in loss of cd4 and drop in %, and.. vice cersa ? Last, in terms of total lymphocites - in the first couple of years post infection does the total lymphocyte count and % have a tendency to increse, or decrease ? I'm guessing increase because of a significant elevation of cd8s which count toward total lymphocytes (?), but this may be incorrect ? Thank you very much for your time and consideration of my question.
| Response from Dr. Holodniy
Yes, in general higher viral loads will result in increased CD8 count. The reverse is not necessarily true. Yes to the CD4%/count question. Generally the total lymphocyte count would increase or stay generally the same.
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