Sep 29, 2007
Is there an accepted set of standards in the medical community one must meet in order to be qualified as a long-term nonprogressor, or is it a much more fluid definition that can vary from doctor to doctor? Ive tried to research specifics, but Ive only come across vague definitions. How many years must one be HIV-positive, and what are the ranges for CD4 counts and viral loads that one must meet in order to receive this designation?
Response from Dr. Holodniy
The name changes as our understanding changes. Elite controllers are those who have relatively high CD4 counts and a viral load < 50 for at least a year in the absence of treatment. Viral controllers are those with detectable viral loads < 2000, stable CD4 counts for some period and not on treatment. Long term nonprogressors are usually those with stable CD4 counts in the normal range, undetectable viral load over at least 5-10 years in the absence of treatment.
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