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Could this be acute/or chronic hep-c
Mar 31, 2007

I am a health care provider.In 1993 I had mild LFT increase ALT 60 hep pannel was neg came back to normal after some time. I also had this in 1997 also hepitis pannel neg once again in 2005 hep pannel neg normal LFT.In feb 2006 I had a colonoscope done in mid april I noted my urine dark LFT 1600 hep pannel neg hep c 0.3 smooth muscle antibody positive,hep B surface antibody 400 core negative (I have had the shots). the following week hepatitis c antibody was 1.3 PCR positive 2.5 mil biopsy done no fibrosis or cirrhosis one month after hep c antibody 45 load 280,000.The GI docs say this is a chronic infection but my immune status is neg HIV,hep b, neg (at the time I found the hight LFT) CD-4 789.HIV DNA proviral was negative I am not on dialysis.I do not have a reason to have supressed antibodys that I can think of.I had been takeing lipitor and diovan witch they say could have made the LFT go up.I think this was an acute event.Do you agree or do you think this was chronic and If so should I be looking at other reasons my antibody did not reaspond?My last HIV-1/2 neg at 7.5 months after do I need to recheck this once more?Thank you for your help.

Response from Dr. Holodniy

I cannot comment on the acuteness of the situation, but chronic HCV infection appears to be present.



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