|Does allergic reactions increase unwanted immune activation?
Mar 24, 2007
I understand that hiv disease involves excessive immune activation, which effectively burns out certain components of the immune system. It is also my understanding that allergic responses involve a type of unwanted immune activation. Is there a relationship between the two? Specifically, is it possible that heightened exposure to allergens might hasten the type of immune activation associated with hiv disease?
| Response from Dr. Holodniy
Excellent question. There are other cells and mediators that are involved in allergic responses in addition to the cells involved in HIV infection. I don't know that we have a good answer for your question and whether HIV disease progression is accelerated in those with chronic environmental allergies.
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