The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

Understanding Your LabsUnderstanding Your Labs
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  • Email Email
  • Glossary Glossary

Why do blood banks want to use PCR?

Apr 7, 2001

There seems to have been some investigations by blood banks attempting to convince the FDA to allow them to use PCR instead of p24. Is the reason for this accuracy or economics (or some of both)?

Response from Dr. Holodniy

The blood banks are using HIV viral load testing to screen blood units under an exemption from the FDA, that allows them to use the test for HIV diagnosis. Donor samples are currently pooled in batches of 10-25 samples and viral load testing is performed on the pool. If the pool is positive, all units are tested separatedly. The sensitivity for picking up HIV infection prior to HIV antibody appearance, is felt to be marginally improved by using viral load testing in this strategy compared to p24 antigen testing.

Undectable to High Viral Load in a Few Months
PCR Testing

  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint