The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

Understanding Your LabsUnderstanding Your Labs
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  • Email Email
  • Glossary Glossary

Viral Load Increase

Sep 3, 2006

My partner was diagnosed HIV positive in 2000, 3 months after initial infection. At that time he was started on a regimen of Sustiva and Combivir. Within 3 months, his viral load was reduced to <50 copies and has remained there until his most recent laboratory visit this month, at which time his viral load was tested to be 235 copies, and a CD count of 575. Does the presence of detectable virus indicate impending failure of the drug combination? And if the viral load continues to rise, would HIV genotyping be a viable option prior to starting a new drug combination?

Response from Dr. Holodniy

Unlikely, but possible, this represents failure of the regimen. It is more likely a reflection of assay variability. I would predict that on the next test it will likely be back to undetectable. However, if it continues to rise, then yes, a genotype test would be in order. Most commercial labs require a viral load of > 1,000 to perform such a test.

Viral load counts
cd4 and vl#

  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint