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High Liver enzymes still after stopping meds

Aug 6, 2006


Thank you for the great site. I was hoping you might give me some insight on a problem I've been having.

About 9 months ago I had to stop my meds (taking without incident) after two years because of high liver enzymes AST=119/ALT=291. Mos t other enzymes where slightly elevated but in the normal range. I also had some abdominal fullness and a ultrasound found nothing but an enlarged liver, with the diagnosis of fatty liver. Well, It's been over 9 months since I've been on any meds, No Hep A/B/C and I've had 5 consecutive liver tests and the enzymes are still elevated AST=59 and ALT=119. My platelets have also dropped to 80. I haven't been drinking (before was only a social drinker) and not taking any recreational or other drugs or pain killers. My Dr. can't explain it, and to make things worse I can feel my liver in my abdomen and back area like it is "full" or something still. So now I need to go in for a liver biopsy.

My question would be, can you give me any explanations to what is happening or insight as I am getting very worried and I'll have to start meds again sooner or later.

Thanks again.

Response from Dr. Holodniy

You don't indicate what HIV meds you were taking, but at this point, a liver biopsy is probably indicated if hepatitis viruses, alcohol, and other meds have been ruled out as a source.

VL and CD4 count
dropping cd4%

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