I have been HIV+ for 22yrs and am currently on no meds. I did take Deca injections but this was over 2months ago. My liver enzyme tests have always been normal. My last set of labs, however, show my AST at 144 IU/L and ALT 366 IU/L . All over liver enzymes are within normal ranges. I was vaccinated for hep C and A. When I was diagnosed 22yrs ago, I was told I already had immunity to hep B which was reconfirmed when I switched doctors 12yrs ago. My doctor is having the test redone, but if it comes back the same, what could I be looking at? I do not drink alchohol and have a reasonably healthy diet. These tests were normal last time they were done 2 months ago

Sounds like an acute increase. Likely causes include hepatitis viruses, medications including over the counter meds (like tylenol)and supplements, alcohol, and recreational drugs. It doesn't sound like most of these are possibilities with you. Anabolic steroids like deca can definitely increase liver enzymes. Just to clarify, there is no vaccine for hepatitis C virus, only A and B.