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Difference in 2 weeks
May 28, 2006

Dear Dr, i am recently diagnosed and I would like to ask you about a difference in my results received from different labs. On 24th of March I had a test in the Netherlands (where I study) CD4: 710 and ViralLoad: 6344 and no durg resistance found. Two weeks later, I travelled back to my home country and took again the same typical exams. My CD4 had decreased to 640 and my ViralLoad has increased to 6700 with drug resistance in a small category of 4 drugs. I don't know if it is important to help you, but with my doctor we have tried to define the day of contamination with no succesful precision. it could be maximum 2 years when I had mononucleosis infection (I can't hope that's the correct translation) or minimum Xmas 2005 where i had a urine infection. I have hear that in some patients the HIV moves faster than in others and therefore I am worried I might belong to this small percentage. Thank you very much in advance

Response from Dr. Holodniy

There is no difference between those two viral load results. They can vary by up to 3-fold (3 times up or down) just based on assay variability. Although your CD4 count looks significantly lower, I would not be concerned and suspect the CD4 percent (a more stable number) is probably the same.



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