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HIV and eosinophils

Apr 30, 2006

Does HIV infect eosinophils, if yes, what will be the significance of the infection in AIDS patients coinfected by parasites that cause eosinophilia

Response from Dr. Holodniy

There is scant literature on this topic. However, there are a couple of papers that demonstrate that eosinophils have CD4 receptors and can be infected with HIV strains in the laboratory. Many patients infected with HIV have a slightly elevated eosinophil count, although there is conflicting data regarding any correlation with CD4 count or viral load. The correlation between HIV infection, parasite infection and eosinophilia is poorly understood.

CD4 count after acute infection
Low CD4 Count

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