Advertisement
The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol
Read Now: TheBodyPRO.com Covers AIDS 2014
   
Ask the Experts About

Understanding Your LabsUnderstanding Your Labs
           
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  
  • Email Email
  • Glossary Glossary


detectability thresholds
Mar 18, 2006

Six months after being infected, my VL was <400, CD4 in the 750s and percentage 38%. (I've written earlier about this, answered on February 12.) The nurse-practitioner I'm seeing is so puzzled that she's ordered a repeat EIA (and, presumably, a confirmatory WB). Are there cases in the literature where someone has "eliminated" HIV from his or her body? I'm not clutching at straws, just scientifically curious. (My EIA and WB were positive in January, with five bands present in the WB.)

Along with the antibody tests, she ordered an ultrasensitive VL test (after all, the level could be 390 or something). But the detectability threshold for this -- it's a Roche PCR version I think -- is 50 copies. Is that standard? I've certainly had friends take tests (in other countries, admittedly, not the US) where the detectability threshold was 20 copies. And I've recently heard that there are ultra-ultrasensitive tests being performed in Europe that can go as low as <5 copies. So: a question about HIV "elimination," another about 50 vs. 20 copies, and a third about superduper-sensitive tests (perhaps approved only for research/lab purposes?).

Thanks again.

Response from Dr. Holodniy

There a small minority of people who are HIV infected and have undetectable plasma levels of viral load, as defined as < 50 copies/ml. Yes, there are assays out there that go down to zero, whatever that means. People will have evidence of HIV infection by detection of HIV in blood or lymph node cells, even in the absence of a detectable blood plasma viral load.



Previous
T-Cell worry
Next
Just a small, affectionate comment

  
  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS


 
Advertisement



Q&A TERMS OF USE

This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint

Advertisement