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No Meds, High CD4, Viral Load all over the place

Mar 11, 2006

Hi there,

I've been HIV+ for about 5years now. I have a CD4 count constantly around the 470 mark, but my Viral Load is all over the place, ranging from 700,000 (the highest) to 42,000, and it seems to jump around all over the place between these two figures. I've never been on Meds as my Doctor sees no need for starting meds as my CD4 is constantly so high. He can't however explain why the Viral Load is so changable. I'm in a monogamous relationship with a HIV- guy (so we always practice safe sex). I have however noticed recently that there is a slight correlation between my weight and my VL count. When I start putting on weight, the VL falls (but I start looking pudgy and unhealthy and I feel so unhealthy). The lowest my VL has been has corresponded with when I was the fattest. When I loose weight, my VL skyrockets, but I look really good and healthy and everyone comments how healthy I look, and I feel so much healthier.

Can weight have such a dramatic impact on VL? What else could make the VL so changable (apart from other viral illness such as colds etc which we've ruled out because many of the bloods have been taken when I was seemingly in perfect health.)?

Response from Dr. Holodniy

I am not aware that weight has been correlated with viral load levels.

assay variability

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