Dec 17, 2005
Does CD4/CD8 inversion occur before/during or after HIV viremia rampup and seroconversion? Can inversion ever be returned to notmal ratio? What causes inversion?
| Response from Dr. Holodniy
Usually happens sometime after infection has been established. The inversion of the ratio is a result of loss of CD4 cells because HIV infects those cells and expansion of CD8 cells in reaction to the HIV infection.
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