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delta 32
Nov 6, 2005

exactly what is the delta 32 gene..how do you know if you have it?

Response from Dr. Holodniy

It is a deletion of 32 bases of DNA in the gene that codes for the R5 receptor that is important in HIV infection. Namely, R5 is a coreceptor that HIV requires in order to lock onto a t helper cell and infect it. If the mutation is present, it changes the structure of the receptor on the cell surface and it is much harder to get infected with HIV. This deletion can be detected with a blood test that is primarily a research tool. It is very unlikely that any major clinical testing labs offer this test.



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