cell counts and percentages
May 13, 2005
I am very keen on understanding some of the measurements done on HIV infected individuals so I have a number of questions to ask. 1.When a CD4 count is done, does this incluced the infected cells. 2. Can a percentage HIV-1specific IL-2 expression in CD4 cells be used as a measure of the number of T helper-1 cells present. Also, how is this % related to the actual number of CD4 helper cells. 3.What is the range for dendritic cell count in a healthy and in HIV infected individual. Thank you.
Response from Dr. Holodniy
1. yes. 2. IL-2 expressing CD4 cells are a subpopulation of the total CD4 cells. Percent can be defined as a percentage of total lymphocytes or of CD4 positive cells if looking at a subset of CD4 cells. 3. There are both myeloid and lymphoid DC in blood with a range of 0.1-0.5% of mononuclear cells, which are in turn about 30% of the white blood cells. They are depressed in HIV infection.
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.