Sep 6, 2004
I am on the regimen of efarinez, ddi and 3tc and was told I'm resistant to 3Tc. This is my first regimen and first resistance test. Can I just switch the 3tc to tenofovir?? What is commonly done in this situation?
| Response from Dr. Holodniy
Data from many studies indicate that 3TC is usually the first drug in a failing regimen to demonstrate resistance. The "184V" mutation by itself does not affect tenofovir activity. It is only when several other mutations (those usually associated with AZT or d4T resistance are present) does tenofovir lose it's activity. Changing to tenofovir in your situation is a reasonable approach. The ddI dose will need to be decreased to 250mg once daily though.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- After Gonorrhea Treatment If Masturbated Does The Medicine Still Work
- Can Thrush Cause A Metallic Taste In Your Mouth?
- How Long Does Hpv Take To Develop?
- Red Brown Clots Discharge And Back Pain, 7 Weeks
- What Can Cause Vaginal Pain In A Toddler?
- 6 Weeks After Exposure I Have A Sore Throat
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.