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neutropenia without meds

Jul 4, 2004

Hi: I've been infected less than two years and am not on any medication of any sort yet. T's 450/19%, vl >100K. I have noticed that my neutrophil count which was a steady 3.2 before infection has dropped to 1.4, apparently as a result of the hiv. Is this something I need to watch and, in particular should I avoid azt in my regimen - likely to come soon -in case it makes things worse?

Response from Dr. Holodniy

It is a little unusual to see this kind of drop in neutrophil count in someone who does not have AIDS, or is not receiving medications that cause bone marrow toxicity. Sometimes when the neutrophil count goes below 500, people become more susceptible to bacterial and fungal infections and require antibiotics for protection. If your count got to this level, I would want to know why and a bone marrow biopsy might be in order. You are correct that AZT might contribute to a further lowering of the the neutrophil count.

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