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CD4 dropped under 500

Jun 20, 2004

Last labs CD4 down from 590 to 388, in approx only 6 months. Previous CD4's have been over 500 for several years. Viral load was 1900 copies, not in yet from most recent. Low level resistance developing. Dr not concerned as he also looks at %'s. As count has dropped more than 1-2% to under 500 I am concerned. Any advice, possible reasons for this? He recommends tests in 3 months and possible med change.

Response from Dr. Holodniy

You don't indicate what the CD4 percentages were with these two values and what the percentage drop was. You indicate that low level resistance is developing. Was a resistance test performed to confirm this? You also indicate that the viral load was 1900. Was it undetectable before and is now 1900? If this is the case and the next viral load is 1900 or higher, and resistance is present, then I think a med change is recommended.

CD cells
VL < 400 but CD4 decline

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