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CD4 going Down
Jun 14, 2004

A friend of mine was diagnosed last summer with HIV. CD4 at time was 350 and VL 50000. He started Sustiva and combivir in November. Since then his CD4 has been going down. Last month CD4 was 295 and VL 17. Whats going on. Please help.

Response from Dr. Holodniy

I need a little more information. Was there a CD4 and viral load done at the time of starting treatment in November(in addition to what was done in the summer)? What was the CD4 percentage at baseline before starting treatment? Do you mean the CD4 percentage was 17, or when you say VL is 17, you mean the viral load is 17. We usually can't quantify viral loads below 50 copies/ml. Lastly, what was the white blood cell count (WBC) and total lymphocyte count at all the blood draws. This additional info is needed to make sense if there is really no treatment response.



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