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Eradicating HIV

May 15, 2004

Since antiviral drugs have the ability to reduce the viral load to undetectable (below 50 copies), then why are we not able to go the "extra mile" to eradicate the virus from the body? Why can't we snuff out the virus completely? What will it take to accomplish that, and is that likely or possible in the near future?

Response from Dr. Holodniy

Because current therapy does not erradicate long-lived t cells that have HIV integrated into their DNA. Thus, a long-term circulating reservoir exists.



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