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HIV-2 screening and re-testing

May 1, 2004

A friend recently had a positive western for HIV-2 (repeated twice). She was screening for a clinical trial in which they look for HIV-1 and -2. Because this is rare in the US, she wanted to ensure the samples were not mixed in the lab. She went to a clinic and was re-screened by an OriQuick. The web site said it can only be used for HIV-1, but the FDA states that it has recently been approved for HIV-2 testing. Would her test picked up the HIV-2, or is the Oriquick HIV-1/2 test a seperate test? Please let me know so I can help advise her in what she should do. Thank you.

Response from Dr. Holodniy

The test was approved for both viruses at the end of March. Why would you want to rescreen with a screening antibody test, when a confirmatory western blot test was repeatedly positive?

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