|How do these T cell subsets compare with the norm?
Apr 11, 2004
Can you please tell me how typical my Lab numbers are and any significance from your perspective?
Infected and dx for 2 years now:
Date CD4 abs CD4 pcntg Ratio
2/2002 900 42 1.01 4/2002 620 36 1 7/2002 900 44 1.1 11/02 1,050 46 1.02 4/2003 780 41 1.01 6/2003 640 33 1 8/2003 1,100 46 1.2 12/2003 1,158 47 1.3 1/2004 1,050 47 1.4
How do the above T cell numbers compare to what is usually seen over a 2 years time frame from infection? I am pleased that my CD4's recovered and that the ratio never dipped below 1. But,the dips by 380 cells in early 2002 and by 410 cells and 13 percent (between end of 2002 and June of 2003) are quite scary- they showed me how rapidly the picture can change....or would you just say they are of no clinical importance as long as CD4's stayed above 500? No RNA VL could be detected during this period either, including by bDNA and the 1.5 assays. But, I did (and do) feel very ill, which is all a mystery.
In any event, I'd much appreciate your advice on the above: is it quite common to have the same number and percent of CD4 cells 2 years after onset of symptoms and Dx, for the CD4/CD8 ratio to never actually invert (though it came close) and for the ratio to have been the highest ever 2 months ago?
| Response from Dr. Holodniy
Your numbers are great. I would not be that concerned about these fluctuations given how high the numbers are. Given those CD4 counts and undetectable viral loads, you are in a very small minority of very fortunate patients.
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