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My globulin calculated level has been the same after infection as this a good or bad thing?

Apr 11, 2004

Before becoming infected with HIV 2 1/2 years ago, my Globulin Calculated was 2.6 (in 1999) and in the 2 1/2 years of infection since early 2002, my Globulin has been exactly at 2.4 to 2.6 (almost always at 2.6),except once last year when it was 3.3...normal lab range being 2.2 to 4.2

Is this unusual to have essentially the same globulin levels before and for 2 1/2 years after HIV infection? Shouldn't globulin levels go above normal if there is a good immune and antibody response to HIV or is the stability of my globulin levels within low normal (from before and after infection) a sign of a strong immune system? Any meaningful clinical information in this situation?

Thank you.

Response from Dr. Holodniy

I am not sure many treating practitioners would be using this number as an indicator of immune system activity. Many, but not all infected people will have some chronic elevation above their baseline.

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Recent HIV: understanding good results

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