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Globulin Calculated and other globulins

Apr 11, 2004

Is the Globulin Calculated level usually much above normal in HIV positive folk?

Mine has been 2.4 to 2.6 through a couple of years, when normal is from 2.2to 4.2. Is this a sign of a less robust immune response to HIV in that higher Globulin usually means a "healthy immune elevation to fight HIV?

Also, how is Globulin Calculated different from alpha 1, alpha 2 globulin, beta globulin and gamma globulin?

Thank you.

Response from Dr. Holodniy

In many, but not all HIV infected people, the serum globulin can be elevated. This is usually a simple chemistry test performed on an automated analyzer. There are more sophisticated measurements that can be obtained to look at the specific components like you have listed.

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